Police said on Sunday that they had charged three men and a woman with murder over the death of a 46-year-old man on Friday.
The suspects are aged between 20 and 37.
They have been accused of killing the 46-year-old man in a flat on Portland Street in Mong Kok. Police were called to the home on Portland Street shortly after midnight on Friday, finding the man unconscious with multiple stab wounds.
He was declared dead at Kwong Wah Hospital soon afterwards.
They were due to appear in the Kowloon City Magistrates' court on Monday morning.
A total of six people have been arrested in connection with the case, including a 34-year-old woman suspected of assisting offenders.
She has been released on bail as investigators continue their probe.
Police earlier said they suspected the case was linked to a dispute over money.