Dozens of people in coup-hit Myanmar's central region were killed in air strikes on Tuesday, according to local media and eye-witness reports.

The country has been in chaos and its economy in tatters since the military seized power in February 2021.

The death toll from the early morning strike on the remote Kantbalu township in Sagaing region is unclear.

At least 50 fatalities and dozens wounded were reported by BBC Burmese, The Irrawaddy and Radio Free Asia.

Sagaing region – near the second-largest city Mandalay – has put up some of the fiercest resistance to the military's rule, with intense fighting raging there for months.

Graphic video clips circulating on social media show bodies scattered among the ruins of homes.

"We are going to rescue you if we hear you screaming," one person can be heard saying in the video. "Please scream!"

A rescuer – connected to an anti-coup People's Defence Force group – said women and children were among the dead.

After recovering bodies and transporting victims for medical treatment, he estimated the death toll could be up to 100.

Before military aircraft strafed Pazi Gyi village, scores of locals had gathered to mark the opening of a local defence force office.

Myanmar's National Unity Government (NUG), a shadow body dominated by former lawmakers from ousted civilian leader Aung San Suu Kyi's party, condemned the strike as a "heinous act".

"We... share the great pain felt by the families affected by this tragedy," it said in a statement.

A spokesperson for the United Nations Special Envoy to Myanmar, Noeleen Heyzer, said agencies were trying to verify the reports.

The military, which accuses anti-coup fighters of being terrorists, has faced international condemnation for razing villages, mass killings and air strikes on civilians.

More than 3,200 civilians have been killed and more than 21,300 arrested since the coup, according to a local monitoring group. (AFP)