US Treasury Secretary Janet Yellen on Thursday sought to reassure Asian countries that the US approach to China would not lead to a "disastrous" division of the global economy that would force them to take sides.

In a speech ahead of the US-hosted Asia Pacific Economic Cooperation (Apec) summit in San Francisco later this month, Yellen said that a full de-coupling of the US and Chinese economies was "simply not practical," especially given the complexity of Asian supply chains and the region's deep economic ties to China.

Her comments sought to assuage growing concerns about geopolitical fragmentation of the global economy into US-led and China-led factions amid growing national security-driven export and technology controls between the world's two largest economies.

"A full separation of our economies, or an approach in which countries including those in the Indo-Pacific are forced to take sides, would have significant negative global repercussions," Yellen said. "We have no interest in such a divided world and its disastrous effects."

Yellen said the US instead was pursuing the "de-risking and diversifying" of its economic ties to China, by investing in manufacturing at home and by strengthening linkages with allies and partners around the world, including Indo-Pacific countries.

Yellen said the US would not compromise on national security actions, but aimed to keep them narrowly targeted, not for the purpose of "choking off growth in China."

Her remarks to an Asia Society event came as the US is preparing to host leaders and other top officials from Apec countries in San Francisco from November 11-17. The White House wants to schedule a meeting between President Xi Jinping and US President Joe Biden on the sidelines of the summit.

Yellen said the Biden administration was committed to expanding trade and investment with Indo-Pacific countries, emphasising the region's strategic importance ahead of the Apec gathering.

Deeper economic links with Indo-Pacific countries will help make US supply chains more resilient and tap into a dynamic and growing market for US exports, she said.

"As we look toward Apec later this month, let me state unequivocally: Claims that America is turning away from the Indo-Pacific are wholly unfounded," Yellen said in the excerpts. "We are deepening our economic ties across the region, with tremendous potential benefits for the US economy and for the Indo-Pacific."

The Biden administration also has called a seventh negotiating round for its Indo-Pacific Economic Framework for Prosperity (IPEF) initiative next week in San Francisco, aimed at reaching some agreements in time for the Apec summit.

The Foreign Ministry on Wednesday said Beijing and Washington had agreed to work together to hold a leaders' meeting in San Francisco. (Reuters, AFP)