Australian media reports on Friday said more than 100 people were believed to have been killed Friday in a landslide that buried a village in a remote part of Papua New Guinea.

The landslide reportedly hit Kaokalam village in Enga province early on Friday morning, about 600 kilometres northwest of the South Pacific island nation's capital of Port Moresby, ABC reported.

Provincial governor Peter Ipatas told international media there had been a big landslide "causing loss of life and property" amid unconfirmed reports that hundreds may be buried.

He later said that "more than six villages" had been hit, describing the scene as an "unprecedented natural disaster" that had caused "substantial damages".

A rapid response team of medics, military, police and UN agencies was dispatched to the area to assess the damage and help the injured. (Agencies)