China on Wednesday called on the international community to prevent the situation in the Middle East from spiralling out of control, following the latest escalation the region.

"The Chinese side calls on the international community, especially major influential powers, to truly play a constructive role and prevent the situation from further deteriorating," a foreign ministry spokesman said in a statement.

"The Chinese side is deeply concerned about the turmoil in the Middle East," the online statement said.

Israel has vowed to make Iran "pay" for firing a barrage of missiles at its territory and warned on Wednesday it would launch an even bigger attack if it is targeted.

Iran launched its second direct attack on Israel in history on Tuesday, firing what it said were 200 missiles, including hypersonic weapons, that sent Israeli civilians into shelters.

China said it "opposes any act that violates Lebanon's sovereignty, security and territorial integrity and opposes the intensification of conflicts".

Hezbollah began low-intensity strikes on Israeli troops a day after its Palestinian ally Hamas staged the October 7 attack, which triggered Israel's devastating assault on Gaza.

"The Chinese side believes that the failure to achieve a ceasefire in Gaza is the root cause of the current turmoil in the Middle East," according to the Foreign Ministry.

"All parties should work for a comprehensive and lasting ceasefire in Gaza as soon as possible." (Xinhua/AFP)