Israeli strikes have killed at least 15 people in the southern Lebanese town of Qana while the Israeli military attacked Beirut's southern suburbs early on Wednesday for the first time in nearly a week.

There was no immediate comment from the Israeli military on the strikes in Qana late on Tuesday.

Lebanon's Civil Defence said 15 bodies had been recovered from the rubble of a building and that rescue efforts were still underway.

Meanwhile, the strikes on southern Beirut were the first in six days, and came after Lebanon's caretaker Prime Minister Najib Mikati said the United States had given him assurances that Israel would curb its strikes on the capital.

There was no immediate word on casualties.

Hezbollah has a strong presence in southern Beirut, known as the Dahiyeh, which is also a residential and commercial area home to large numbers of civilians and people unaffiliated with the militant group.

The Israeli military said it targeted an arms warehouse under a residential building.

It posted an evacuation warning on the X platform ahead of the strike, saying it was targeting a building in the Haret Hreik neighbourhood.

Hezbollah began firing rockets into Israel on October 8 in solidarity with the Palestinian militant group Hamas, following the surprise Hamas attack on southern Israel that triggered the war in Gaza.

A year of low-level fighting along the Israel-Lebanon border escalated into all-out war last month , and has displaced some 1.2 million people in Lebanon.

Some 2,300 people have been killed by Israeli strikes in Lebanon since last October, more than three-quarters of them in the past month, according to Lebanon's Health Ministry. (AP)