The Commerce Ministry said China will resolutely take countermeasures and fight till the end if the United States insists on further escalating economic and trade restrictive measures, with firm will and abundant means.
"I want to emphasise that there is no winner in a trade war, and China does not want a trade war, but the Chinese government will by no means sit by when the legitimate rights and interests of its people are being hurt and deprived," an official with the ministry said.
The comments came as US tariffs of 104 percent for Chinese goods came into force on Wednesday.
The official also said Beijing hopes Washington will immediately remove its unilateral imposition of tariffs, and work with China to strengthen dialogue, manage differences and promote cooperation.
Under the guise of pursuing "reciprocity" and "fairness," the US is engaging in zero-sum games and, in essence, seeking "America First" and "American exceptionalism," the official said.
Noting that the US is also deliberately severing the well-established global industrial and supply chains and breaking the market-oriented free trade rules, the official said these practices seriously interrupt the economic development of countries around the globe and affect the long-term stable growth of the world economy.
Meanwhile, Foreign Ministry spokesman Lin Jian told a regular briefing that "the Chinese people's legitimate right to development is inalienable".
"China's sovereignty, security and development interests are inviolable," he said. "We will continue to take firm and forceful measures to safeguard our legitimate rights and interests." (Xinhua & agencies)