US President Donald Trump on Wednesday signed an executive order suspending US support for 66 organisations, agencies and commissions, following his administration’s review of participation in and funding for all international organisations, including those affiliated with the United Nations, according to a White House release.

Most of the targets are UN-related agencies, commissions and advisory panels that focus on climate, labour, migration and other issues the Trump administration has categorised as catering to diversity and “woke” initiatives.

Other non-UN organisations on the list include the Partnership for Atlantic Cooperation, the International Institute for Democracy and Electoral Assistance and Global Counterterrorism Forum.

“The Trump Administration has found these institutions to be redundant in their scope, mismanaged, unnecessary, wasteful, poorly run, captured by the interests of actors advancing their own agendas contrary to our own, or a threat to our nation’s sovereignty, freedoms, and general prosperity,” the State Department said in a statement.

Trump's decision to withdraw from organisations that foster cooperation among nations to address global challenges comes as his administration has launched military efforts or issued threats that have rattled allies and adversaries alike, including capturing Venezuelan leader Nicolás Maduro and indicating an intention to take over Greenland.

This is the latest US withdrawal from global agencies. The administration previously suspended support from agencies like the World Health Organization, the UN Human Rights Council and the UN cultural agency Unesco as it has taken a larger, a-la-carte approach to paying its dues to the world body, picking which operations and agencies they believe align with Trump’s agenda and those which no longer serve US interests.

“I think what we’re seeing is the crystallisation of the US approach to multilateralism, which is ‘my way or the highway,’” said Daniel Forti, head of UN affairs at the International Crisis Group.

“It's a very clear vision of wanting international cooperation on Washington’s own terms.”

Many independent nongovernmental agencies – some that work with the United Nations – have cited many project closures because of the US administration’s decision last year to slash foreign assistance through the US Agency for International Development, or USAID. (AP)