Miami Dolphins quarterback Tua Tagovailoa's concussion problems returned on Thursday as he was taken out of his team's 31-10 home loss to divisional rivals Buffalo Bills.

Tagovailoa, who had endured a miserable night throwing three interceptions, was hurt with 4:24 remaining in the third quarter and with his team already 31-10 down.

Running with the ball on a fourth down, Tagovailoa lowered his head into the body of Bills defensive back Damar Hamlin.

After receiving on-field treatment, the 26-year-old quarterback left the field under his own power and peaking to Dolphins staff. Miami later confirmed he had been taken out and replaced by Skylar Thompson due to a concussion.

Tagovailoa endured a series of injuries during the 2022 season, including two documented concussions which raised questions over his long-term future in the game, but stayed injury-free last season.

The injury came after Buffalo had emphatically shown they have no intention of giving up their domination of the AFC East, looking far superior to their rivals in all areas.

The Bills, led by quarterback Josh Allen, have won the last four AFC East divisional titles and Allen now has an 11-2 record against the Dolphins.

Tagovailoa's injury adds fresh concerns over his durability, on a night when Buffalo showed they remain a cut above their closest divisional rivals in recent seasons. (AFP)